Overview
Introduction
A low absolute neutrophil count changes the meaning of an otherwise modest symptom.
A low absolute neutrophil count changes the meaning of an otherwise modest symptom. Neutrophils normally provide rapid defence against bacterial and fungal invasion, so a neutropenic client may deteriorate before producing pus, redness, or swelling. Fever can be the only visible clue. For the RN, the priority is to recognise the febrile-neutropenia pattern, obtain ordered cultures promptly, escalate deterioration, and ensure prescribed empiric antimicrobial therapy is not delayed. Antimicrobial selection and prescribing are prescriber-led; the RN assesses, initiates the urgent response within local policy, administers treatment safely, and reassesses the client’s response.